The off-label use of ketamine to treat chronic pain is not supported by scientific evidence, a new Cochrane review has found

We are pleased to welcome new members to the Cochrane Methods Executive!

Meet Danielle, member of our Patient and Public Network Executive team. This month, April English, our Patient and Public Involvement Manager had the honour of sitting down with Danielle to talk about her motivations to getting involved, the impact it’s had, top tips, and much more.

Cochrane is piloting two living evidence gap maps in 2025 to map primary research and systematic reviews in two urgent areas of global health.

As systematic reviewers, we synthesize the best available evidence to inform the decisions of the public, patients, clinicians, and policy makers. But what happens when the evidence is fatally flawed? Lisa Bero argues that systematic reviewers are uniquely positioned – and ethically obligated – to detect problematic studies and champion research integrity.

Discover more information about our new interactive learning module on rapid reviews, designed to support researchers and health decision-makers who need to produce high-quality evidence quickly and efficiently.

We are committed to addressing the challenges associated with AI with an approach that is measured and responsible. Discover the work we are doing to ensure AI is used responsibly in evidence synthesis.

Rose, a recent medical graduate from Egypt, found her passion for evidence-based medicine through Cochrane’s learning resources and is now actively contributing to systematic reviews and The People's Review. Discover more about her experiences.

A Cochrane review has found that virtual reality (VR), when used in addition to standard therapy, can help stroke survivors regain arm movement. The findings suggests that VR could be a promising tool to boost rehabilitation efforts.

Cochrane launches its first-ever volunteer strategy, developed in response to feedback from more than 1900 people who are either currently volunteering, or interested in getting involved.

Read our reflections on a week of historic milestones and inspiring dialogue at the 78th World Health Assembly (WHA), the world’s foremost global health policy event.

A newly-published Cochrane review reveals significant gaps in the clinical rating scales used to assess pain in newborn babies, highlighting the urgent need for improved tools and global collaboration.