A new review including over 100 clinical trials has found that no induction method was clearly effective than low-dose vaginal misoprostol, although some methods were less effective and safety profiles varied.

For more than 30 years, Cochrane has championed the involvement of patients and the public in shaping health evidence, and this commitment remains just as strong today. In 2025, we took significant steps to embed PPI more deeply into our work.

From preventing complications in pregnancy to improving outcomes for the world’s youngest children, our work reflects the disparities in maternal, newborn and child health that still persist today. For Maternal Health Awareness Day, we take a look at some of Cochrane's achievements in this area, and our plans for the future.

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There is no clear evidence that cannabis-based medicines provide pain relief for chronic neuropathic pain, an updated Cochrane review finds.

This month, we’re sharing the full interview with Alex Todhunter-Brown, author of the Cochrane review Physical rehabilitation approaches for the recovery of function and mobility following stroke.

Image  Join us behind the scenes for reflections, best practices and impact stories from author teams, Geographic Groups, and others involving patients and the public in Cochrane activities.  

Exercise may reduce symptoms of depression to a similar extent as psychological therapy, according to an updated Cochrane review. When compared with antidepressant medication, exercise also showed a similar effect, but the evidence was of low certainty.

Yasmine is a member of the Patient and Public Network and a Cochrane US Year 4 trainee. Yasmine began by contributing to plain language summaries through Cochrane Engage and is now part of a global research project. She shares where this had lead.

Free or subsidized school meals lead to modest gains in math and school enrolment, according to a new Cochrane review that examined the global impact of school feeding programs on disadvantaged children in both high-income countries and low- and middle-income countries.

An updated Cochrane review has found that calcium supplementation has no effect on pre-eclampsia, challenging long-held assumptions about the role of calcium in preventing hypertensive disorders in pregnancy.

Learn about HPV as we answer common questions and explore how vaccination can protect children.

Two new Cochrane reviews show strong and consistent evidence that HPV vaccines are effective in preventing cervical cancer and pre-cancerous changes, especially when given to young people before they are exposed to the virus.

Guyane joined Cochrane through a local project with Cochrane Canada. Our Patient and Public Involvement Manager, April English, sat down with Guyane to talk about motivations to getting involved, the impact it’s had, top tips, and much more.

Cochrane invites proposals from AI tool developers to participate in a pilot initiative aimed at transforming how we produce and share high-quality evidence syntheses. This is an exciting opportunity to collaborate with a globally trusted organization in health research and contribute to the future of systematic reviews.

Decisions about the HPV vaccine among adolescents and their families are influenced by a web of social, cultural and trust-related factors, beyond simple awareness or access

Vaccination against human papillomavirus (HPV) is one of the most effective tools for preventing cervical cancer in women and other HPV-associated diseases in people of all genders. Yet many people worldwide remain reluctant to take the vaccine.

A widely-used, inexpensive gout drug could reduce heart attacks and strokes in people with cardiovascular disease, according to a new Cochrane review.

Cochrane, the Campbell Collaboration, JBI, and the Collaboration for Environmental Evidence have published a joint position statement on the responsible use of artificial intelligence (AI) in evidence synthesis.

Three new Cochrane reviews find evidence that GLP-1 drugs result in clinically meaningful weight loss, but industry-funded studies raise questions.